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Woman cancer-free after UK’s first liver tranplant for advanced bowel cancer | UK News

A 32-year-old woman is cancer-free after undergoing the UK’s first liver transplant for advanced bowel cancer.

Bianca Perea, a trainee lawyer from Manchester, was diagnosed with the most advanced kind of bowel cancer in November 2021, with doctors telling her they aimed to prolong her life rather than find a cure.

But, alongside other treatments including targeted drug therapy, chemotherapy and surgery, the transplant has been a huge success and Ms Perea now has no signs of cancer anywhere in her body.

Ms Perea first visited her GP in Wigan after feeling constipated and bloated. After tests, a colonoscopy and a biopsy, she was diagnosed with stage four bowel cancer, which had spread to all eight segments of her liver.

Ms Perea accepted the diagnosis, but said she refused to believe the outlook was so bleak.

“I don’t want to sound kind of ignorant or arrogant or anything like that but I just didn’t feel in my gut that that was going to be it,” she said.

Her mother asked about a possible transplant at that stage but was told it was not a feasible treatment.

Ms Perea had 37 rounds of a targeted drug called panitumumab plus chemotherapy for two and a half years.

She had an excellent response to the treatment, which meant she was able to have an operation in May 2023 to remove the bowel tumour.

But scans showed she still had tumours in her liver, which could not be operated on.

EMBARGOED TO 0001 MONDAY JANUARY 6 Undated handout photo issued by The Christie NHS Foundation Trust of Bianca Perea who is cancer-free after undergoing the UK's first liver transplant for advanced bowel cancer. Bianca, a 32-year-old trainee lawyer from Manchester, was given the surgery in the hope it could offer a potential cure for her deadly disease. Issue date: Monday January 6, 2025.
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Bianca with her beloved dog. Pic: PA

Nevertheless, because her response to chemotherapy had been so good and her bowel cancer was seemingly gone, doctors began to look at liver transplants.

Ms Perea was added to the transplant list in February 2024 and was lucky enough to find a donor last summer.

File photo dated 30/11/17 of an NHS Blood and Transplant Small Human Organ in Transit box at St George's Hospital in Tooting, west London. Some 35 human organs were made available for transplant after being donated over Christmas Eve and Christmas Day, new figures have shown. The organs were provided by 11 donors across the UK after their death and included a heart, lungs, kidneys, livers, pancreas and bowel, NHS Blood and Transplant (NHSBT) said. Issue date: Friday December 27, 2024.
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An NHS Blood and Transplant Small Human Organ in Transit box at St George’s Hospital in Tooting, west London. File pic: PA

She said: “Within four weeks of going under the knife, I was able to drive and walk the family dogs, it was really quite incredible.

“To go from being told I’d only have a short time to live to now being cancer-free is the greatest gift.

“I’ve been given a second chance at life and I’m going to grab it with both hands. I am so grateful to the family who agreed to donate their loved one’s liver.

“I do believe this is a cure. They’re always hesitant to say that, obviously, but I am cancer-free right now.”

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Now, Ms Perea is looking forward to going on holiday this year and is working on improving her fitness.

“My liver is doing really well,” she said. “I get tests on that, and I’ve just had my second scan and that’s all clear, so it’s really good.”

Dr Kalena Marti, Ms Perea’s oncologist, said: “To see that Bianca has had such a positive outcome is wonderful.

“When we looked at the tumour cells in her liver after it had been removed, they weren’t active.

“This is excellent news, and we hope that this means that the cancer won’t come back.”

She added: “Advanced bowel cancer is complex and there are lots of different types of the disease, so what works for one person might not work for another. As a result, it’s important that we continue to develop new treatments.

“Thanks to the generosity of organ donors and their loved ones, we can now access liver transplants for some patients, which is fantastic.”

You can watch a full interview with Ms Perea at 8.30am this morning on Sky News Breakfast.

Next in advanced talks to snap up vintage brand Cath Kidston | Business News

Next is in advanced talks to buy Cath Kidston in its latest swoop on a prominent but troubled retail brand.

Sky News has learnt that the FTSE-100 chain, which has a market value of close to £8.7bn, could wrap up a deal to acquire the modern vintage label as soon as Tuesday.

Banking sources said an agreement was likely but not certain.

Cath Kidston has been owned by Hilco Capital, the specialist retail investor, for less than a year.

Next’s prospective swoop on it marks a further attempt to build a portfolio of wholly owned retail labels.

Its acquisition strategy has focused on well-known names which have run into financial difficulties and which can benefit from Next’s logistics and marketing muscle.

Among the brands it has bought are Made, the online furniture retailer, and Joules, the fashion group which collapsed into administration late last year.

It also bid for TopShop, the then jewel in the crown of Sir Philip Green’s high street empire, but pulled out of an auction before the brand was sold to ASOS.

Next is due to report full-year results on Wednesday and is forecast by City analysts to unveil record pre-tax profits of more than £850m.

PricewaterhouseCoopers has been advising Hilco on a sale of Cath Kidston for several weeks, and is understood to have held talks with a number of potential bidders.

Cath Kidston has been owned by Hilco Capital for less than a year
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Cath Kidston has been owned by Hilco Capital for less than a year

Cath Kidston was bought out of administration little more than two years ago by Baring Private Equity Asia (BPEA).

At one stage, it had scores of shops, but now trades from fewer than a handful of its own outlets, having collapsed into administration in 2020 with the loss of nearly 1,000 jobs.

It was established by its eponymous founder in 1993, and became a high street fixture with scores of standalone shops.

Like many retailers, however, its fortunes were hit by the pandemic, forcing it into insolvency about three years ago.

BPEA, which took full control of Cath Kidston in 2016, struck a pre-pack insolvency deal which entailed the closure of its UK high street estate.

It still has fewer than a handful of stores in Saudi Arabia.

Known for its floral and polka dot designs, Cath Kidston has been run for several years by Melinda Paraie, who joined as chief executive from luxury goods brand Coach in 2018.

It expanded from a single shop in west London selling car boot finds and vintage fabric into a business offering fashion, homewares and accessories.

The chain made a fortune for its founder when she sold a stake to private equity firm TA Associates about 12 years ago in a deal reportedly worth £100m.

Next and Hilco declined to comment.