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‘Speed is of the essence’: Liz Hurley encourages people to see a doctor if they think they have breast cancer | Ents & Arts News

One woman will be diagnosed with breast cancer every 10 minutes in this country and one man every day and yet until the 1990s it wasn’t a topic for discussion. Ever.

Evelyn Lauder, whose mother-in-law Estee Lauder founded the famous cosmetics company of the same name, was one of the first to change that.

Co-creator of the pink ribbon in 1989, a few years later Lauder signed up the actress and model Liz Hurley to be the global ambassador for the Estee Lauder Companies’ Breast Cancer Campaign.

The move helped open up the breast cancer conversation.

Hurley, whose grandmother died of breast cancer, tells Sky News: “I think we’ve come a long way in the years that I’ve been with Estee Lauder Companies’ breast cancer campaign.

“Certainly when the campaign was started 30 years ago there was virtually no awareness of breast cancer.

“The pink ribbon hadn’t been invented. October as Breast Cancer Awareness Month didn’t exist.

“When my grandmother was diagnosed in the early 90s she found her own lump and was mortified and embarrassed and didn’t tell anyone including her doctor for about a year by which time unfortunately it had spread. So that’s why this campaign was started to try and make breast cancer not something that was whispered but shouted about.”

And yet despite all the publicity every October, 10% of women never check their breasts and two in five rarely do.

They think it will never happen to them but Hurley says that’s a big risk.

She continues: “Unfortunately one in eight of us will get breast cancer in our lifetime. So it’s sort of playing the odds quite dramatically if you think you won’t be one of those eight.

“I think it’s probably better when you’re of the age to get screened, which is 50 plus in the UK, and I personally believe because I know so many women who found their own lumps in their own breasts when they’re younger, that I feel it would be good advice to check your breasts regularly.

“But I think knowing that mortality rates have dropped more than 42% since the late 80s is because treatments are better, treatments are targeted and most breast cancers are found earlier.”

Breast cancer remains a taboo subject in some Asian and African communities, where cancer treatment can amongst other things affect fertility.

Hurley says: “‘It’s very important for us to learn about these difficulties. Different types of breast cancer affect different types of women very differently. And we’re finding out more and more about that and putting more and more of our research money actually into studies to examine how breast cancer can affect diverse communities.”

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Hurley sat down for an interview with Jacquie Beltrao
Image:
Hurley sat down for an interview with Jacquie Beltrao

Going to the GP quickly can be the key to surviving this disease, which still kills 11,500 women in the UK every year, or 31 every day.

And if you find a lump it will be acted upon.

Hurley continues: “‘From the women I’ve spoken to if they found a lump in their breasts the NHS deals with it very quickly in taking them to the next stage, which is biopsy.

“Most people sort of know their bodies and we know if something doesn’t feel right.

“It might not be something as tangible as a lump. It could just be feeling bad and then in that case you have to be very firm and try and get as many tests as you can – at the very least a blood test. I would advise people if they feel something is wrong to be as persistent as you can with your doctor.”

Scientists are closer to finding a cure than they were 10 years ago but they are not there yet.

Hurley says: “The fact that there’s targeted treatments now means women are more likely to survive today than in the past. But everything hinges on early detection, for a breast cancer to be found early and it’s still localised there’s more than a 90% chance of survival.

“I would say be breast aware, familiarise yourself with your own breasts. Be aware of any changes and don’t be afraid to go to the doctor. Quickly. Speed is of the essence.”

AI tools can ‘safely’ read breast cancer scans, preliminary study suggests | Science & Tech News

Artificial intelligence (AI) can “safely” read breast cancer screening images, a preliminary study suggests.

Researchers found computer-aided detection could spot cancer in mammograms – X-ray pictures of the breast – at a “similar rate” to two radiologists.

The NHS is already looking at how it can implement such technology in its breast screening programme.

However, the authors of the study said the results are “not enough on their own to confirm that AI is ready to be implemented in mammography screening”.

Previous studies into whether AI can accurately diagnose breast cancer in mammograms have been carried out retrospectively – where the technology assesses scans already examined by doctors.

But the new interim study pit AI-supported screening against standard care.

The randomised control trial, published in the journal Lancet Oncology, involved more than 80,000 women from Sweden with an average age of 54.

Half of the scans were assessed by two radiologists, known as standard care, while the other half were assessed by the AI-supported screening tool, followed by interpretation by one or two radiologists.

In total 244 women from AI-supported screening were found to have cancer compared with 203 women recalled from standard screening.

Also, the use of AI did not generate more “false positives” – where a scan is incorrectly diagnosed as abnormal. The false-positive rate was 1.5% in both the AI group and the group assessed by radiologists.

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AI could halve screening workload

Researchers said the use of AI could potentially almost halve the screening workload.

There were 36,886 fewer screen readings by radiologists in the AI-supported group compared with the group who received standard care, resulting in a 44% reduction in the screen-reading workload of radiologists, the authors said.

The study is continuing to assess whether AI tools can reduce cancers diagnosed between screenings, with the results not expected for a few years.

But the authors’ interim analysis concludes: “AI-supported mammography screening resulted in a similar cancer detection rate compared with standard double reading, with a substantially lower screen-reading workload, indicating that the use of AI in mammography screening is safe.”

Radiologists could be ‘less burdened by excessive amount of reading’

Lead author Dr Kristina Lang, from Lund University in Sweden, said: “These promising interim safety results should be used to inform new trials and programme-based evaluations to address the pronounced radiologist shortage in many countries, but they are not enough on their own to confirm that AI is ready to be implemented in mammography screening.

“We still need to understand the implications on patients’ outcomes, especially whether combining radiologists’ expertise with AI can help detect interval cancers that are often missed by traditional screening, as well as the cost-effectiveness of the technology.”

She added: “The greatest potential of AI right now is that it could allow radiologists to be less burdened by the excessive amount of reading.

“While our AI-supported screening system requires at least one radiologist in charge of detection, it could potentially do away with the need for double reading of the majority of mammograms, easing the pressure on workloads and enabling radiologists to focus on more advanced diagnostics while shortening waiting times for patients.”

NHS exploring implementing AI

Commenting on the study, an NHS spokesperson said: “The NHS is already exploring how AI could help in breast screening by enabling complicated image analysis very quickly and at scale, which, if proven effective, could in future help speed up diagnosis for many women, detect cancers at an earlier stage, and ultimately save more lives.

“This research is very encouraging, and plans are underway to assess the best ways of implementing this technology into the NHS Breast Screening Programme.”

Gene mutation which increases risk of breast and ovarian cancer linked to Orkney islands | UK News

A gene mutation which increases the risk of breast and ovarian cancer has been linked to people with Orkney heritage.

Scientists from the universities of Aberdeen and Edinburgh have found that one in one hundred people with grandparents from the islands off the north-eastern coast of Scotland, have a mutation of the gene BRCA1.

It is likely the gene variant came from one of the founding members of Westray – an Orkney island which has a population of under 600 people – at least 250 years ago, according to the research.

The gene mutation was repeatedly spotted in women from Orkney who have the cancers, most of whom could also trace their family ancestry back to the small island of Westray.

As a result of the findings, planning is under way to offer free testing for the gene variant to anyone living on the Scottish islands with a Westray-born grandparent, regardless of their family history with the disease.

Professor Zosia Miedzybrodzka, director of NHS North of Scotland Genetic Service, made it clear that developing cancer is not solely down to carrying the BRCA1 variant alone.

What is a BRCA1 gene?

Genes are found in every cell in our body. They enable bodies to grow and function correctly.

BRCA1 is a tumour suppressor gene that helps to protect us from developing cancer, according to the NHS.

A variation can affect the function of the gene. This can increase the chance of developing breast, ovarian or prostate cancer, which is more likely to occur at a younger age.

A person’s genes can be examined from a blood sample. However, currently, it is usually only offered to families with a strong history of cancers.

Everyone has the BRCA genes, but not everyone has mutations in them.

“There are many complex factors, and some people with gene alterations will not get cancer,” Prof Miedzybrodzka said. “However, we know that testing and the right follow-up can save lives.”

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She recommended things like risk-reducing surgery, breast screening with MRI from the age of 30 and lifestyle advice to improve the health of women with the gene mutation.

Awareness of the faulty gene was raised when Hollywood actress Angelina Jolie underwent a double mastectomy a decade ago, after losing her mother to ovarian cancer and then discovering she had a BRCA1 variant.

The NHS recommends talking to your GP if cancer runs in the family, or if you are worried about your own risk. They may refer you for a genetics test, which will tell you if you have inherited one of the cancer risk genes.