Search for:
kralbetz.com1xbit güncelTipobet365Anadolu Casino GirişMariobet GirişSupertotobet mobil girişBetistbahis.comSahabetTarafbetMatadorbethack forumBetturkeyXumabet Girişrestbetbetpas
BioNTech cancer treatments deal is a coup for the government and a challenge for the NHS | Science & Tech News

BioNTech has signed a deal with the UK government to enrol up to 10,000 patients in clinical trials by the end of 2030 for personalised cancer therapies.

The deal is a big win for the UK, yet new cancer treatments will only work if the NHS does.

Vaccines based on mRNA were the standout success of the COVID-19 pandemic. And persuading BioNTech, the company which pioneered them, to come to the UK is a coup for the Department of Health.

But with even basic cancer services in the UK failing, experts are tempering their enthusiasm.

“This is really exciting,” says Sam Godfrey of Cancer Research UK. “But the government can’t just paper over the cracks with a shiny new announcement.”

More than 600 million of doses of the Pfizer/BioNTech COVID vaccine have now been administered worldwide saving millions of lives. During the pandemic, BioNTech proved mRNA vaccines’ time has come.

Which is why a deal with BioNTech is a strategic success for the government.

The pandemic exposed the UK’s lack of commercial expertise in mRNA vaccines. This deal, along with one last month with leading mRNA vaccine company Moderna, secures that talent base in the UK.

Designing mRNA vaccines against cancer is a very different challenge to COVID. But before the pandemic, cancer was the main area of research for BioNTech and Moderna.

Because mRNA is basically a re-coded form of DNA, it’s relatively quick and easy to convert a sample of DNA from a patient’s cancer into an mRNA vaccine to give them. But so far immunotherapies aren’t perfect.

For a few, they’re a miracle cure, but overall only 10 and 20% of patients see benefits.

For drug companies, the NHS offers a perfect environment to work out the scientific kinks in cancer vaccines.

Millions of patients centralised in one health system make them much easier to recruit and follow in potentially life-saving clinical trials.

Read more:
Pioneering cancer vaccine trials could start in UK by September
COVID cases: Infections leap to six-month high after Christmas as one in 20 test positive in England

Yet with delays to cancer diagnoses and treatment, the NHS is struggling to provide existing treatments, let alone have much hope of benefitting from new ones.

And the problem isn’t all down to the pandemic. NHS England’s target of getting 85% of patients on to treatment within 62 days of an urgent cancer referral hasn’t been met since 2015.

Leading the world in developing new cancer treatments requires a world-leading health service, which it is all too clear we currently don’t have.

Denial of alleged coup attempt and ex-PM’s arms deal bid revealed in declassified documents | UK News

Details of an alleged government coup attempt and a prime minister’s desperate bid for an arms deal have been revealed in a slew of freshly declassified documents.

The secretive records have been released for the first time by the National Archives in Kew.

Among them is a letter surrounding a reported plot to overthrow Harold Wilson’s Labour government in 1968.

The story had enough weight to be recreated for Netflix royal drama The Crown, but correspondence from one of those accused years later described it as “nonsense” with “no foundation in fact”.

Those were the words of publishing guru Cecil King in a 1981 note to Whitehall mandarin Sir Robert Armstrong, as he dismissed claims he had conspired with Lord Mountbatten – the Duke of Edinburgh’s uncle – and Lord Cudlipp.

Mr King, chairman of the International Publishing Corporation (IPC) which counted the Daily Mirror among its titles, accused Mr Wilson of feeding the coup allegation to the press years after he was legitimately ousted by Ted Heath’s Conservatives in 1970.

The alleged coup was reported in The Times newspaper, prompting the then prime minister Margaret Thatcher to address the claims in parliament.

Decades later, it formed part of season three of The Crown.

An embittered Mr King suspected that the accusation played a part in his removal from the IPC.

“Unlike most newspaper stories this one had no foundation in fact,” he said in his letter.

(Original Caption) 1978-London, England- Margaret Thatcher, leader of the British Conservative Party, is on the threshold of becoming Britain's first woman Prime Minister. Mrs. Thatcher wears dark blue dress with white collar, background is dark.
Margaret Thatcher was forced to address the reports

Composer loved by royals ‘sought help with illegal drug supply’

Also revealed is how a revered British composer beloved by the Royal Family secretly sought state help to supply him with illegal quantities of controlled drugs.

Sir William Walton, whose famous composition Crown Imperial was used in the Queen’s Coronation in 1953 and the Platinum Jubilee celebrations this year, was said to be “very dependent” on Ritalin, commonly used to treat ADHD.

Records show his wife, Lady Susana Walton, asked a police inspector in 1982 to help send a year’s supply to his home on the island of Ischia, near Naples, in Italy.

Sending such high volumes of the substance abroad was illegal, but his wife asked anyway because – the records suggest – she “rather lives with her head in the clouds”.

UK knew of French president’s secret health woes

Another revelation released by the National Archives is that the UK government knew the extent of ailing French president Francois Mitterrand’s ill-health a decade before his terminal prognosis was made public.

Diplomat Sir Reginald Hibber filled in Whitehall colleagues in December 1981 with “talk about the President’s health which seemed to me to carry a certain amount of conviction”.

Sir Reginald suggested Mr Mitterrand may have cancer, less than a year after he had taken office.

That proved to be correct, as Mr Mitterrand died in 1996 with prostate cancer – something he successfully concealed from the French public throughout his presidency – which ended in 1995 – and until his death.

Britain's Prime Minister Tony Blair speaks to the media on the second day of the European Union heads of state and governments summit in Brussels December 15, 2006. REUTERS/Yves Herman (BELGIUM)
Tony Blair’s bid for an arms deal with Kuwait is also detailed in the documents

Blair begged Kuwait for arms deal

According to other declassified records, Tony Blair begged Kuwait to buy UK artillery as payback for supporting the Middle Eastern nation during the Gulf War.

He repeatedly lobbied Crown Prince Sheikh Sa’ad between 1998 and 1999, even calling in on him during a brief stopover on a flight home from South Africa to press the point.

Internal briefing notes show the government believed it was “due the award of a significant defence equipment contract in recognition of its defence of Kuwait” following the invasion of Saddam Hussein’s Iraqi forces in 1990.

The efforts did not immediately reap rewards, as Kuwait announced its intention to buy US artillery instead.