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Dec 3 2024

‘Pioneering’ drug for rare eye cancer to be rolled out on NHS in England | Science, Climate & Tech News

Hundreds of people in England with a rare form of eye cancer are set to have access to a “pioneering” drug, the NHS has announced.

Following approval by the National Institute for Health and Care Excellence (NICE), patients diagnosed with uveal melanoma can now be offered a drug called tebentafusp.

The cancer is thought to affect between 500 and 600 people in the UK each year, and develops from cells in the middle layer of the eye.

Once it has spread to major organs, the disease is almost always fatal, according to the NHS.

NICE announced on Tuesday that it has recommended tebentafusp – sold under the brand name Kimmtrak – for patients whose uveal melanoma cannot be removed with surgery, or has spread to other parts of the body.

They will need a blood test to determine if they have the genetic markers that make them suitable for the treatment. More than 100 people each year are expected to be eligible.

Joanne Foster, who was diagnosed with uveal melanoma in 2013, said she was offered tebentafusp last year through a compassionate access scheme after the cancer spread to her lungs and kidneys.

The 57-year-old from Newcastle said her disease is “both physically and mentally draining,” and added: “I’ve had my eye removed and ongoing treatment for over a decade, with the uncertainty of not knowing what is round the corner being incredibly difficult, particularly with no treatments available until now.

“The news that tebentafusp is now available for hundreds of current and future NHS patients just like me is the best early Christmas present I could’ve asked for.

“While I know it isn’t a long-term cure, it has shrunk the tumour on my kidney and stabilised my cancer in my lungs, which gives me precious time to spend with my family and loved ones.”

The drug works by attaching to the proteins on the surface of cancer cells and T cells, a type of white blood cell

It helps the immune system recognise and kill cancer cells, slowing the growth of the disease.

According to NHS England, trials have shown the chance of surviving three years after starting tebentafusp is 27% compared with 18% on the current standard treatment checkpoint inhibitors.

Overall survival on tebentafusp was also 21.6 months, compared with 16.9 months.

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Professor Peter Johnson, NHS national clinical director for cancer, said: “It is great news that the NHS can now offer this pioneering treatment, giving people an option that can extend their lives and offer them valuable extra time with their families and friends”.

Jo Gumbs, CEO and founder of Ocular Melanoma UK, said: “Today’s announcement that tebentafusp will be available for people with metastatic uveal melanoma is simply incredible.”

She added: “For too long, metastatic uveal melanoma has been a devastating cancer so we look forward to many more improvements in the future so every patient has access to the treatments they need.”

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Dec 1 2024

Starmer to outline his 'plan for change' focusing on schools, NHS and efficiency

Sir Keir Starmer is set to reveal his Labour’s “plan for change” as he looks to draw a line under a tough first five months in office amid public anger over budget proposals.

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Nov 2 2024

NHS pilots new iPhone adapter to check patients for throat cancer | UK News

The NHS has begun trialling a new iPhone adapter which can check whether someone has throat cancer.

It is hoped the device will allow thousands of patients to be given the all-clear from the disease within hours – rather than days or weeks – as well as helping to detect cases early.

People suspected of having throat cancer are usually given an endoscopy, which involves a long, thin tube with a camera inside being passed through their mouth or nose to look inside their body.

The endoscope-i adapter, which can be attached to one of Apple’s smart phones, includes a 32mm lens endoscope eyepiece and an accompanying app.

It allows nurses to capture endoscopy footage in high definition before sharing it with specialists who can report back to patients directly.

The NHS said an initial pilot by the North Midlands University Hospitals NHS Trust had helped reassure more than 1,800 low-risk patients that they did not have throat cancer, with those tested receiving their results “within 23 hours”.

The gadget also helped detect cancer in around one in a hundred of those tested.

Officials said no cancers were missed during the trial.

A spokesperson said it could be used more widely across the country “in diagnostic centres and community settings”, reducing the need for patients to go to hospitals, freeing up resources and reducing waiting times.

Dr Cally Palmer, national cancer director at NHS England, said: “Detecting cancer early is key to providing treatment as soon as possible to help give patients the best chance of survival.

“For those needing tests to investigate suspected cancer, it can be an extremely worrying time and being able to rule out the disease sooner can make a huge difference for people and their families.”

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There are around 250,000 urgent referrals for suspected head and neck cancer each year, according to NHS England.

However, only 5% of these are diagnosed with the disease.

Janet Hennessy, 76, from Stoke-on-Trent, said she thought the device was “absolutely brilliant” after she took part in the trial.

She added: “When you have a procedure done and you’ve got to go back home and wait two or three weeks, even if you think there’s nothing there, you’re still thinking about it and it worries you and your family.”

Meanwhile, Kyle Jones, 31, was diagnosed using the gadget after being referred to Royal Stoke Hospital by his GP.

He said: “I remember being confused at the time due to my only symptom being a hoarse voice. It was like I had been singing too much at a gig the night before.”

Mr Jones said it was a “massive shock” to be informed he had cancer but was reassured by medics. He had his voicebox removed to prevent the disease from spreading further.

He added: “I’m scared to even think where I’d be or what could have happened without this device.

“With how fast that my cancer developed after the first appointment to the stage where I needed a big laryngectomy surgery it makes me so grateful that it was picked up and in time and I believe that has saved my life.”

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Oct 21 2024

Government calls on British public to share experiences and ideas to ‘help fix our NHS’ | Politics News

The British public and clinicians are being asked to share their experiences and ideas to “help fix our NHS”.

Health Secretary Wes Streeting is calling on the entire country to help shape the government’s “10 Year Health Plan” with a “national conversation”.

Members of the public, NHS staff and experts are being invited to share their experiences, views and ideas on how the health service should move forward.

People can submit their ideas on change.nhs.uk or on the NHS app until the beginning of next year.

Mr Streeting, who was treated for kidney cancer in 2021, said the NHS “saved my life” and everyone owed the health service “a debt of gratitude”.

“Now we have a chance to repay that debt,” he said.

“Today the NHS is going through the worst crisis in its history. But while the NHS is broken, it’s not beaten.

“Together, we can fix it.

“Whether you use the NHS or work in it, you see first-hand what’s great, but also what isn’t working. We need your ideas to help turn the NHS around.”

The project is part of what the government is calling a shift “from hospital to community”.

It will include plans for new neighbourhood health centres where patients will be able to see GPs, district nurses, care workers, physiotherapists, health visitors and mental health specialists in the same place.

They also want to change the NHS “from analogue to digital” by putting all patient health information, test results and letters on the NHS app.

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New laws will be introduced, the government says, to make NHS patient records available across all NHS trusts, GP surgeries and ambulance services in England to speed up patient care, reduce repeat medical tests and minimise medication errors.

The government estimates NHS staff will save 140,000 hours every year as they will be able to access patient data quickly, giving them more time to spend with patients.

As part of Labour’s plan to move “from sickness to prevention”, it is looking at opportunities to shorten the amount of time people are ill, and to prevent illnesses.

One of the options being considered is handing out smart watches and other wearable tech to patients with diabetes or high blood pressure so they can monitor their health at any time.

Sir Keir Starmer said the 10 Year Health Plan is a “huge opportunity to put the NHS back on its feet”.

“So, let’s be the generation that took the NHS from the worst crisis in its history and made it fit for the future,” he added.

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Liberal Democrat leader Sir Ed Davey urged the government to show “ambition” in its plans, or risk the consultation “becoming a talking shop”.

He said: “We know that primary care services across the country are at the brink of collapse due to the Conservative Party’s disgraceful neglect, with patients paying the price.

“Whether it is sky-high GP waiting lists, endless ambulance response times, or a failure to diagnose cancer in time, none of these issues can be fixed without fixing the crisis in social care.

“That is why the Liberal Democrats will make sure that social care is part of the debate and push for a cross-party solution to this crisis.”

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Sep 12 2024

Tories ‘squandered golden inheritance on NHS’, says Wes Streeting – ahead of Sir Keir Starmer’s ‘reform or die’ speech | Politics News

The Tories “squandered a golden inheritance” on the NHS, the health secretary has said – as he laid out three “fundamental shifts” to fix it.

Wes Streeting told Sky News Tony Blair’s Labour government left the health service with the lowest waiting times and highest patient satisfaction “in the history of the NHS”.

“What’s criminal is that in the last 14 years, the Conservatives took that golden inheritance and squandered it. And they don’t bear any responsibility,” he said.

Politics live: PM to pledge ‘biggest reimagining of NHS’ in major speech

Mr Streeting was speaking after an independent report he commissioned found the NHS is in a “critical condition”, with record waiting lists and too much of its budget spent in hospitals.

Off the back of the investigation, Prime Minister Sir Keir Starmer will give a speech today in which he will warn the health service must “reform or die” and set out a 10-year plan to fix it.

Giving a flavour of what that could look like, Mr Streeting said the NHS needed three “fundamental” changes.

That includes a “shift from hospital to community”, so people are diagnosed earlier and faster; greater investment in technology to create a “digital NHS”; and dealing with sickness in society.

He said: “That’s why today’s report was so important, because, ironically, although it’s looking back on how we got here and diagnosing the illness, it’s actually helping us to look forward and be honest about how we got here.”

The study, carried out by peer and surgeon Lord Darzi, argues the NHS is facing rising demand for care as people live longer in ill health, coupled with low productivity in hospitals and poor staff morale.

It criticises political decision-making under the Conservatives and the coalition government, including the impact of austerity, a “starvation of investment” and the reorganisation of the NHS under the 2012 Health and Social Care Act, which Lord Darzi called “a calamity without international precedent”.

This meant the COVID pandemic came “when resilience was at an all time low”, he said.

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Mr Streeting likened the findings to the Conservatives “not just failing to fix the roof while the sun was shining, but effectively pouring petrol on the house, turning the gas on”.

“And then the pandemic lit the match,” he added.

Asked how a report of such magnitude can be compiled in nine weeks, Mr Streeting said Lord Darzi spoke to frontline staff, leaders and thinktanks and was also given “unfettered access” to NHS and Department of Health data.

In other morning interviews, he warned the NHS would “go bust” if it was not reformed, but ruled out raising money through a salt or sugar tax.

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Shadow health secretary Victoria Atkins told Sky News she had “never shied away” from the NHS’s problems during her time in office, when asked if she was embarrassed about the state her party left it in.

She accused Labour of “trying to get headlines” by trailing out the report, calling instead for a “proper conversation about what we do with the NHS”.

Lord Darzi, a former Labour health minister turned independent peer, ultimately argued the NHS can be fixed, saying his findings do not question “the principles of a health service that is taxpayer-funded, free at the point of use”.

Later this morning, the prime minster will set out his plans for the “the biggest reimagining of our NHS since its birth”.

He will say this won’t be “easy or quick” but “sticking plaster solutions” won’t do.

He will say: “Working people can’t afford to pay more, so it’s reform or die.”

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Sep 12 2024

Darzai review: Key points from damning new report into state of NHS | Politics News

A major report on the health service has been published in which it is described as being “in serious trouble”.

The rapid review by Lord Darzi was completed in just nine weeks and sets out the problems in the NHS and themes for the government to incorporate into a 10-year plan for reforming the health service.

Lord Darzi, a widely respected surgeon and former health minister, insisted the NHS can be fixed.

His report detailed the following issues:

• The health of the nation has deteriorated, with more years spent in ill health. Contributing factors – over the past 15 years – include poor quality housing, low income and insecure employment. The result is the “NHS has faced rising demand for healthcare from a society in distress”.

• There has been a “surge” in multiple long-term conditions, including a rise in poor mental health among children and young people. Fewer children get their vaccines and fewer adults now participate in things such as breast cancer screening.

• Waiting times targets are being missed across the board, including for surgery, cancer care, A&E and mental health services. “Long waits have become normalised” and “A&E is in an awful state”.

• People are struggling to see their GP. “GPs are seeing more patients than ever before, but with the number of fully qualified GPs relative to the population falling, waiting times are rising and patient satisfaction is at its lowest ever level.”

• Cancer care still lags behind other countries and cancer death rates are higher than in other countries. There was “no progress whatsoever” in diagnosing cancer at stage I and II between 2013 and 2021. However, more recent figures show some improvement.

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• Progress in cutting death rates from heart disease has stalled while rapid access to treatment has deteriorated.

• The NHS budget “is not being spent where it should be” and too great a share is being “spent in hospitals, too little in the community, and productivity is too low”. Too many hospital beds are taken up with people needing social care.

• Between 2009 and 2023 the number of nurses working in the community fell by 5%, while the number of health visitors dropped by nearly 20%.

• At the start of 2024, 2.8 million people were economically inactive due to long-term sickness, with most of the rise since the pandemic down to mental health conditions.

• Raids on capital budgets have left the NHS with crumbling buildings and too many outdated scanners, and “parts of the NHS are yet to enter the digital era”.

• The NHS delayed, cancelled or postponed far more routine care during the pandemic than any comparable health system.

• Too many NHS staff are “disengaged” and there are “distressingly high levels of sickness absence”.

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Sep 7 2024

‘Too many children being let down’ by NHS, new report expected to warn | Politics News

A new government commissioned report into the state of the NHS is expected to reveal new figures on the treatment of children, finding that “too many are being let down”.

It comes as the prime minister, in his first major interview since entering Number 10, has told the BBC that the previous government “broke” the NHS in ways which are “unforgivable”.

Speaking to the BBC’s Laura Kuenssberg in the Downing Street Cabinet Room, he said a review of the health service to be published this week finds the Conservatives’ changes to the NHS were “hopelessly misconceived”.

The report, by leading cancer surgeon and former health minister Lord Darzi, is expected to reveal that more than 100,000 infants up to the age of two were left waiting for more than six hours in A&E departments in England last year.

It is also expected to warn of a 60% rise in waiting times for that age group over the past 15 years, and 800,000 children and young people on NHS waiting lists for hospital treatment.

Some 175,000 were waiting between six and 12 months, and 35,000 waiting for more than a year, the report is expected to say.

He also uncovered that nearly 500,000 children and young people were on waiting lists for mental health support and that 160,000 of them had been waiting for over 12 months.

NHS is ‘broken’

Speaking ahead of the report’s publication, Sir Keir said: “The impacts of a broken NHS are being felt across the whole of our society – our children included.

“The challenges we’ve inherited are stark, but I’m determined to fix the foundations so that we not only rebuild our health service, but crucially also reform and renew it for the benefit of future generations.

“That also means equipping the NHS to prevent ill health, not just to treat it – so that all of us can live longer, healthier lives, from childhood to old age.”

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And in a TV interview, the prime minister said: “Everybody watching this who has used the NHS, or have relatives who have, know that it’s broken, they know that it’s broken, that is unforgivable, the state of our NHS.”

On the reasons for the crisis, Sir Keir said: “The money that was taken out of the NHS, particularly in the early years of the coalition from 2010 onwards, the Lansley reforms, which were hopelessly misconceived, and then of course COVID on top of all that, which has put us in this awful position for the NHS.”

He added: “It’s the last government that broke the NHS. Our job now, through Lord Darzi, is to properly understand how that came about and bring about the reforms, starting with the first steps – the 40,000 extra appointments. But we’ve got to do the hard yards of reform as well.”

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Aug 7 2024

UK riots: People who are racist to NHS staff ‘can and should’ be refused care, health secretary says | UK News

People who are racist to NHS staff “can and should” be turned away, the health secretary has said.

Wes Streeting condemned “mindless thuggery” seen across Britain in the aftermath of the Southport stabbings over the past week.

As far-right violence spread between towns and cities, Filipino nurses were attacked on Friday night as they travelled to work for emergency cover during unrest in Sunderland.

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Speaking to the PA news agency, Mr Streeting said the people who attacked them “brought enormous shame on our country”.

According to reports, the taxi they were travelling in was pelted with rocks and they were left “terrified”, the Mirror reported, though they were physically unharmed.

“I will not tolerate, under any circumstances, NHS or social care staff in any health or care setting being subjected to intimidation, harassment or racist abuse,” Mr Streeting said.

“We have a zero-tolerance policy in the NHS and we’ll take a zero-tolerance approach in social care too.

“People who are abusing NHS staff can be turned away, and should be turned away, if that is the way that they are treating our staff.”

He added the country is “lucky” to have people in the NHS who “come from around the world to provide great, compassionate care”.

“I am proud that we have those people in Britain. I think the vast majority of Brits are too,” he said.

“And those people that have hijacked our flag for their mindless, racist thuggery – they have no idea about this country’s history or heritage, and they have brought enormous shame on our country by attacking NHS staff in this way.”

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Professor Nicola Ranger, general secretary and chief executive of the Royal College of Nursing, said guidance on when and how patients can be refused care has been updated.

It comes after GP leaders issued a warning to family doctors amid reports staff had been “targeted” during attacks.

Family doctors and their teams have been urged to “remain vigilant, particularly when travelling to and from work”.

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The Royal College of GPs (RCGP) highlighted “horrific and unacceptable” abuse and violence towards healthcare workers, “especially those from ethnic minorities”.

The RCGP urged staff to travel in groups “where possible” and to try to avoid areas where there is known unrest.

Meanwhile, two GP surgeries in northeast London have said they are planning to shut early on Wednesday because of potential unrest in the area.

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Jun 9 2024

Electric headset for treating depression recommended as widespread treatment after NHS trial | UK News

An electric headset for treating depression has been recommended as a more widespread treatment for depression after a successful NHS trial. But it’s not yet known what the long term benefits of the device are.

An NHS trial has found that an innovative electric headset for treating depression is an effective way of reducing the symptoms, and has recommended its more widespread use within the health service.

The headset from Flow Neuroscience was given to patients with depression by their GP to wear for 30 minutes daily for a period of six weeks, as a non-invasive way to manage the condition.

The study found that it was an “effective depression treatment”, by using a brain stimulation technique known as transcranial direct current stimulation, or tDCS.

The device delivers a weak direct electrical current to the front of the brain, to stimulate the areas responsible for emotional expression.

The research found over 58% of people saw improvements within six weeks, and one in three went into remission with no depression symptoms.

Flow Neuroscience says it’s the “first and only medically approved at home treatment for depression”, and it can be used alongside other therapies like talking therapies or drugs.

It was trialled on patients by Northamptonshire NHS Foundations Trust, but it can also be bought privately for £399.

One of those patients is James Maynard, who has struggled with depression prior to using the headset.

He told Sky News: “I was just so low, I didn’t really have any goals and would just go through the emotions of day-to-day life.

“Going to work, coming home from the children, going to sleep. If I could sleep.”

After just a few weeks of wearing the device every day for 30 minutes, he says his symptoms noticeably improved.

“I was starting to sleep a bit better. The wife even said I was happier. I wasn’t waking up grumpy. So there was obviously something happening.”

One of the NHS Trial Leads is Dr Azhar Zafar, who told Sky News that patients report having to use fewer medications as a result of the device.

He says: “It’s a new option because for years and years, we will have only the option of medication or a cognitive behavioural therapy. This method of treatment is an additional treatment.”

It’s not yet known, however, what the long term benefits of the device are on depression past six weeks.

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GP Dr Anita Raja told Sky News that “when it comes to mental health one of the most important things is understanding what the relapse of the patient may be once the treatment stops or is withheld”.

She says this device is promising, but she wants to know “what happens when the patient stops using the device – do they become depressed again?”.

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Jun 8 2024

Endometriosis patient is one of millions waiting for NHS treatment, as numbers have soared | UK News

Jasmine is in so much pain she can hardly get out of bed.

She’s clutching a hot water bottle and taking morphine, a strong painkiller which she says turns her into “a zombie”.

“It’s like there’s like a ball of acid in the middle of my torso and it’s burning its way through each of my organs. And it feels like that 24/7,” said the 23-year-old.

The pain Jasmine is describing is caused by endometriosis, a debilitating condition where cells similar to the ones lining the womb are found elsewhere in the body.

This can lead to inflammation, pain and the formation of scar tissue.

“It feels like there’s just searing, stinging, burning pain constantly. And that’s not even the worst of it,” she tells me.

She said symptoms started when she was about 12 years old and have worsened as the years have gone on.

For years she has had appointments, consultations and surgery on the NHS. But her experiences have left more than physical scars.

“I’ve been made to feel like I’m taking up their time. I’ve been made to feel like I’m not important and that my issues should just be medicated and that’s it.”

Read more: The search for a cure for endometriosis

Jasmine waited a year and seven months for an operation, but only after surgery was cancelled six times.

“There was never really a good explanation as to why the surgery was cancelled. I’d just get called up by someone and told it wasn’t happening.”

7.5 million waiting for treatment

Jasmine is one of millions of patients waiting months, sometimes years for NHS treatment. And the numbers have soared since the pandemic.

The number of people waiting for treatment on the NHS has doubled to 7.5 million and even though targets state that 92% of patients should begin treatment within 18 weeks, that target has not been met for nearly a decade.

Which is why the NHS will be one of the big issues for voters in the general election.

Labour said it will cut NHS waiting times with 40,000 more evening and weekend appointments each week, paid for by cracking down on tax avoidance and non-doms.

Meanwhile, the Conservatives and Lib Dems have also promised to cut waiting lists by pouring an extra £1bn into the NHS.

Tackling waiting lists is also the public’s top priority – the highest number of those polled, 39%, say reducing them is the thing they most want the next government to deliver for the NHS, followed by 26% saying making it easier to get a GP appointment.

Twenty-five per cent who responded said the NHS is completely broken, with 61% saying it’s in a poor state and parts of it are broken. Only 1% of people said the NHS is healthy and has very few problems.

Thirty-two per cent of people said they most trusted Labour to reduce waiting times, with just 9% saying they trust the Conservatives most to do it.

Most tellingly, just over a quarter of those who responded, 26%, said no party can be trusted to solve the problems with the NHS.

‘Life seems quite bleak now’

It currently takes an average of eight years and 10 months to get a diagnosis of endometriosis, according to the charity Endometriosis UK.

Since the start of the COVID-19 pandemic, gynaecology waiting lists have increased by over 60%, the biggest increase in any specialism. In England alone, there are nearly 600,000 people on gynaecology waiting lists.

An NHS spokesperson said: “The NHS takes endometriosis very seriously and it is essential that staff support women experiencing cyclical pain as well as the psychological effects associated with their symptoms.

“The health service is committed to meeting women’s individual healthcare needs and is rolling out dedicated pelvic health clinics – bringing together specialist healthcare staff – to provide further support for women living with endometriosis, as well as supporting all local areas to develop a women’s health hub, to help deliver better menstrual health services and improve women’s health outcomes.”

Jasmine is still waiting for her operation to ease her symptoms of endometriosis.

“It has taken a massive physical toll. But I suppose mentally maybe worse. Life seems quite bleak now. I used to have a lot of dreams wanting to travel the world. But I don’t have the energy for that anymore.”

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She says she hopes whoever wins the general election focuses more on the NHS.

“I’d like to believe that there was some sort of superhero to swoop in and save the NHS but I don’t feel in this current climate that that’s even remotely possible.

“I think the current government have run the NHS into the ground, but I don’t have much faith in any of the other parties to do much better.”

Anyone feeling emotionally distressed or suicidal can call Samaritans for help on 116 123 or email jo@samaritans.org in the UK. In the US, call the Samaritans branch in your area or 1 (800) 273-TALK.

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